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+0.4) and MCS (+0.5 vs
The antigens are associated to MHC II molecule that interacts with T-cell receptor of T CD4 + lymphocytes, leading the antigen recognition and, subsequently, activation
Las potenciales explicaciones incluyen diferencias en el tipo de pacientes incluidos, la adherencia al tratamiento del estudio, el tamao muestral, la duracin de la exposicin al frmaco y la activacin del receptor GLP1 con una mayor reduccin de HbA1c con anlogos basados en GLP1 humano de accin ms prolongada que con algunos anlogos de exendina 4 de accin corta
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Lancet 351 : 13931396 Heron-Milhavet L, LeRoith D (2002) Insulin-like growth factor I induces MDM2-dependent degradation of p53 via the p38 MAPK pathway in response to DNA damage
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